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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM2
All Species:
23.03
Human Site:
Y485
Identified Species:
56.3
UniProt:
P50570
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50570
NP_001005360.1
870
98064
Y485
L
I
D
I
E
Q
S
Y
I
N
T
N
H
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103119
870
98099
Y485
L
I
D
I
E
Q
S
Y
I
N
T
N
H
E
D
Dog
Lupus familis
XP_542065
865
97464
Y485
L
I
D
I
E
Q
S
Y
I
N
T
N
H
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P39054
870
98127
Y485
L
I
D
I
E
Q
S
Y
I
N
T
N
H
E
D
Rat
Rattus norvegicus
P39052
870
98212
Y485
L
I
D
I
E
Q
S
Y
I
N
T
N
H
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
L317
L
S
A
Q
Y
Q
S
L
L
S
S
Y
G
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
Y481
L
I
D
F
E
L
A
Y
M
N
T
N
H
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P39055
830
93389
Y452
C
A
D
T
M
A
R
Y
P
R
L
R
D
E
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
I408
E
D
L
T
A
D
D
I
R
T
A
I
Q
N
A
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
G385
N
F
I
S
S
I
D
G
T
S
S
D
I
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
95.1
N.A.
98.1
98
N.A.
N.A.
N.A.
N.A.
32.9
N.A.
64.4
N.A.
61.9
N.A.
Protein Similarity:
100
N.A.
100
97.2
N.A.
99
99.1
N.A.
N.A.
N.A.
N.A.
51
N.A.
76.9
N.A.
76.5
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
73.3
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
86.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.5
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
10
10
0
0
0
10
0
0
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
70
0
0
10
20
0
0
0
0
10
10
0
60
% D
% Glu:
10
0
0
0
60
0
0
0
0
0
0
0
0
80
0
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% H
% Ile:
0
60
10
50
0
10
0
10
50
0
0
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
70
0
10
0
0
10
0
10
10
0
10
0
0
0
10
% L
% Met:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
60
0
60
0
20
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
0
10
0
60
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
10
10
0
10
0
0
0
% R
% Ser:
0
10
0
10
10
0
60
0
0
20
20
0
0
0
0
% S
% Thr:
0
0
0
20
0
0
0
0
10
10
60
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
70
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _